The clinical pathology of heartwater (3): changes in blood-clotting, blood calcium, blood protein, hematocrit and white-cell counts in sheep with experimentally-induced heartwater

Vanamstel, S. R. and Reyers, Fred and Myburgh, E. and Pretorius, G. and Sacks, P. (1994) The clinical pathology of heartwater (3): changes in blood-clotting, blood calcium, blood protein, hematocrit and white-cell counts in sheep with experimentally-induced heartwater. Onderstepoort Journal of Veterinary Research, 61 (1). pp. 21-27. ISSN 0030-2465

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Abstract

Studies to evaluate changes in blood clotting, blood calcium and protein, the haematocrit and white-cell counts were undertaken in seven sheep with experimentally induced heartwater. A marked decline in thrombocyte count was recorded during the acute stage of the disease. This was associated with increases in both prothrombin time (PT) and activated partial thromboplastin time (APTT); fibrinogen increased while there was no detectable increase in fibrinogen degradation products (FDP). At the same time total serum protein (TSP), albumin and globulin dropped very sharply; total calcium showed a progressive drop but ionized calcium rose initially and was followed by a terminal decline. The total leucocyte count showed a terminal increase while the haematocrit dropped progressively.

Keywords:Sheep diseases
Subjects:D Veterinary Sciences, Agriculture and related subjects > D323 Animal Pathology
D Veterinary Sciences, Agriculture and related subjects > D300 Animal Science
Divisions:College of Science > School of Life Sciences
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ID Code:8810
Deposited On:14 May 2013 08:44

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