The clinical pathology of heartwater (I): hematology and blood chemistry

Amstel, S. R. Van and Reyers, Fred and Guthrie, A. J. and Oberem, P. T. and Bertschinger, H. (1988) The clinical pathology of heartwater (I): hematology and blood chemistry. The Onderstepoort Journal of Veterinary Research, 55 (1). pp. 37-46. ISSN 0030-2465

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Item Type:Article
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Abstract

Clinical pathological studies were undertaken in 5 calves with experimentally-induced heartwater. The most important findings include a progressive anaemia which may be associated with bone marrow depression and fluctuations in the total and differential white cell count, of which an eosinopenia and a lymphocytosis were the most marked. A severe drop in serum protein, especially in the albumin levels, was observed in all 5 cases. This disease is probably associated with an increased capillary permeability, as the protein content of the pericardial fluid in 1 case that died, approximated that of the serum. The osmolality of the effused fluid was also higher than that of the blood. No significant changes in the serum electrolyte levels occurred, except for total calcium levels which tended to decrease to below normal during the acute stage of the disease. Marked increases in total bilirubin were recorded. This, however, was not associated with liver pathology or haemolysis and may possibly be ascribed to a fasting hyperbilirubinaemia. Darkening of plasma colour was associated with peak rises in total bilirubin. Increases in both blood urea and creatinine levels indicate interference with renal glomerular filtration during the acute stage of the disease.

Keywords:Sheep diseases
Subjects:D Veterinary Sciences, Agriculture and related subjects > D323 Animal Pathology
D Veterinary Sciences, Agriculture and related subjects > D300 Animal Science
Divisions:College of Science > School of Life Sciences
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ID Code:8802
Deposited On:14 May 2013 08:44

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