WO/2011/018665 Complexing system

Medical Research Council (2011) WO/2011/018665 Complexing system. .

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Abstract

The invention relates to a complexing system comprising two polypeptide helices derived from a SNAP protein; one polypeptide helix derived from syntaxin; one polypeptide helix derived from synaptobrevin or a homolog thereof; and one or more cargo moieties attached to the polypeptide helices, wherein the four polypeptide helices can form a stable SNARE complex. The invention also relates to a method of producing the complexing system and the use of the complexing system.

Item Type:Patent
Additional Information:The invention relates to a complexing system comprising two polypeptide helices derived from a SNAP protein; one polypeptide helix derived from syntaxin; one polypeptide helix derived from synaptobrevin or a homolog thereof; and one or more cargo moieties attached to the polypeptide helices, wherein the four polypeptide helices can form a stable SNARE complex. The invention also relates to a method of producing the complexing system and the use of the complexing system.
Keywords:SNAREs proteins, Botulinum neurotoxin
Subjects:C Biological Sciences > C710 Applied Molecular Biology, Biophysics and Biochemistry
Divisions:College of Science > School of Life Sciences
ID Code:6588
Deposited By: Enrico Ferrari
Deposited On:15 Oct 2012 20:36
Last Modified:26 Feb 2013 22:37

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