Aloysius, Mark M. and Zaitoun, Abed M. and Bates, Timothy E. and Albasri, Abdulkader and Ilyas, Mohammad and Rowlands, Brian J. and Lobo, Dileep N. (2009) Complete absence of M2-pyruvate kinase expression in benign pancreatic ductal epithelium and pancreaticobiliary and duodenal neoplasia. BMC cancer, 9 . p. 327. ISSN 1471-2407

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Abstract

Elevated serum concentrations of M2-pyruvate kinase (M2-PK) correlate with poor prognosis in patients with pancreaticobiliary and duodenal cancer, but the expression of M2-PK in formalin-fixed pancreatic tissue is unknown. We aimed to characterise the immunohistochemical expression of M2-PK in archived specimens of pancreaticobiliary and duodenal cancers, premalignant lesions, chronic pancreatitis, and normal pancreas.

Item Type:	Article
Keywords:	M2-pyruvate kinase, pancreatic cancer, duodenal neoplasia, epithelium neoplasia, immunohistochemistry, ref03, refdoi
Subjects:	A Medicine and Dentistry > A300 Clinical Medicine B Subjects allied to Medicine > B130 Pathology
Divisions:	College of Sciences > Faculty of Science > School of Life Sciences
Depositing User:	Timothy Bates
Date Deposited:	25 Jun 2012 21:46
Last Modified:	08 May 2013 13:28
URI:	http://eprints.lincoln.ac.uk/id/eprint/5192

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