Immunohistochemical expression of mitochondrial membrane complexes (MMCs) I, III, IV and V in malignant and benign periampullary epithelium: a potential target for drug therapy of periampullary cancer?

Aloysius, Mark M. and Zaitoun, Abed M. and Bates, Timothy E. and Ilyas, Mohammad and Constantin-Teodosiu, Dumitru and Rowlands, Brian J. and Lobo, Dileep N. (2010) Immunohistochemical expression of mitochondrial membrane complexes (MMCs) I, III, IV and V in malignant and benign periampullary epithelium: a potential target for drug therapy of periampullary cancer? BMC Cancer, 10 . p. 80. ISSN 1471-2407

Full content URL: http://www.biomedcentral.com/1471-2407/10/80

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Item Type:Article
Item Status:Live Archive

Abstract

Mitochondrial membrane complexes (MMCs) are key mediators of cellular oxidative phosphorylation, and inhibiting them could lead to cell death. No published data are available on the relative abundance of MMCs in different periampullary cancers. Therefore, we studied the expression profile of MMCs I, III, IV and V in periampullary cancers, reactive pancreatitis, normal pancreas and chronic pancreatitis.

Keywords:pancreatic cancer, periampullary, mitochondrial complexes, malignant, benign, cancer
Subjects:A Medicine and Dentistry > A300 Clinical Medicine
B Subjects allied to Medicine > B130 Pathology
Divisions:College of Science > School of Life Sciences
ID Code:5190
Deposited On:26 Jun 2012 06:04

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