Charge-coupled imagers for time-resolved macromolecular crystallography

Allinson, Nigel M. and Colapietro, M. and Helliwell, J. R. and Moon, K. J. and Thompson, A. W. and Weisgerber, S. (1992) Charge-coupled imagers for time-resolved macromolecular crystallography. Review of Scientific Instruments , 63 (1). pp. 664-666. ISSN 0034-6748

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Abstract

There exists considerable promise for the use of charge‐coupled device (CCD) imagers in the fast recording of parts of macromolecular crystal Laue diffraction patterns. As part of this development CCD tests have been made with direct detection of Laue patterns from a small molecule test crystal and a protein crystal. Merging R factors (on intensity), for strong reflections, of 3% have been obtained. A time‐slicing scheme for a CCD camera is discussed based on the stacking of slices held in storage in the CCD in the submillisecond time resolution range.

Item Type:Article
Additional Information:There exists considerable promise for the use of charge‐coupled device (CCD) imagers in the fast recording of parts of macromolecular crystal Laue diffraction patterns. As part of this development CCD tests have been made with direct detection of Laue patterns from a small molecule test crystal and a protein crystal. Merging R factors (on intensity), for strong reflections, of 3% have been obtained. A time‐slicing scheme for a CCD camera is discussed based on the stacking of slices held in storage in the CCD in the submillisecond time resolution range.
Keywords:Crystallography, macromolecular, CCD Detector
Subjects:F Physical Sciences > F131 Crystallography
Divisions:College of Science > School of Computer Science
ID Code:4907
Deposited By: Tammie Farley
Deposited On:18 Feb 2012 14:50
Last Modified:13 Mar 2013 09:04

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