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Reversing microcrystalline tests: an analytical approach to recycling of microcrystals from drugs of abuse

Elie, Leonie and Baron, Mark and Croxton, Ruth and Elie, Mathieu (2011) Reversing microcrystalline tests: an analytical approach to recycling of microcrystals from drugs of abuse. Forensic Science International, 207 (1-3). e55-e58. ISSN 0379-0738

Full content URL: http://dx.doi.org/10.1016/j.forsciint.2011.01.008

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Reversing microcrystalline tests - an analytical approach to recycling of microcrystals from drugs of abuse
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Item Type:Article
Item Status:Live Archive

Abstract

A combined analysis of microcrystalline tests followed by LC-MS or GC-MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was done to quantify the recovery of the drug. Examples were performed using the date rape drug γ-hydroxybutyrate (GHB) and the synthetic opioid methadone.

Keywords:microcrystalline test, Drugs of abuse, LC-MS, GHB, Methadone
Subjects:F Physical Sciences > F151 Pharmaceutical Chemistry
F Physical Sciences > F100 Chemistry
F Physical Sciences > F180 Analytical Chemistry
Divisions:College of Science > School of Life Sciences
ID Code:3957
Deposited On:08 Feb 2011 20:08

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