Waugh, David and Lawrence, Jonathan (2010) Wettability analysis of CO2 laser surface patterned nylon 6,6 samples soaked in simulated body fluid (SBF). In: Proceedings of the 36th International MATADOR Conference 2010. Springer-Verlag, Berlin, pp. 465-468. ISBN 9781849964319

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Abstract

Simulated body fluid (SBF) has been used previously by others to aid in predicting the bioactivity and osseointegration potential of materials. This paper details a study carried out using a CO2 laser to induce a number of surface patterns which inherently modified both the surface chemistry and surface topography giving rise to a difference in apatite response between each sample. These induced patterns gave rise to a reduction in hydrophilicity with contact angles of up to +10° being observed. Furthermore, following immersion in SBF for 14 days each sample was weighed revealing an increase in weight of up to 0.029 g indicating that an apatite layer had begun to form. In addition, energy dispersive X-ray analysis identified the presence of calcium and phosphorous, two elements which support osteoblast cell response. When comparing with an as-received sample it was found that the laser induced patterned samples gave rise to more layer crystals forming suggesting a more optimized surface for osteoblast cell growth and proliferation.

Item Type:	Book Section
Additional Information:	Simulated body fluid (SBF) has been used previously by others to aid in predicting the bioactivity and osseointegration potential of materials. This paper details a study carried out using a CO2 laser to induce a number of surface patterns which inherently modified both the surface chemistry and surface topography giving rise to a difference in apatite response between each sample. These induced patterns gave rise to a reduction in hydrophilicity with contact angles of up to +10° being observed. Furthermore, following immersion in SBF for 14 days each sample was weighed revealing an increase in weight of up to 0.029 g indicating that an apatite layer had begun to form. In addition, energy dispersive X-ray analysis identified the presence of calcium and phosphorous, two elements which support osteoblast cell response. When comparing with an as-received sample it was found that the laser induced patterned samples gave rise to more layer crystals forming suggesting a more optimized surface for osteoblast cell growth and proliferation.
Keywords:	CO2 laser, nylon 66, wettability, SBF., bmjtype
Subjects:	F Physical Sciences > F361 Laser Physics J Technologies > J410 Polymers Technology H Engineering > H673 Bioengineering
Divisions:	College of Sciences > Faculty of Science > Lincoln School of Engineering
Depositing User:	David Waugh
Date Deposited:	14 Jan 2011 13:52
Last Modified:	13 Mar 2013 08:53
URI:	http://eprints.lincoln.ac.uk/id/eprint/3827

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