Neural network modeling of voluntary single joint movement organization. II. Parkinson’s disease

Cutsuridis, Vassilis (2010) Neural network modeling of voluntary single joint movement organization. II. Parkinson’s disease. In: Computational neuroscience. Springer Optimization and Its Applications, 38 . Springer-Verlag, pp. 193-212. ISBN 9780387886299, 9780387886305

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Abstract

The organization of voluntary movement is disrupted in Parkinson’s disease.
The neural network models of voluntary movement preparation and execution
presented in the previous chapter are extended here by studying the effects of
dopamine depletion in the output of the basal ganglia and in key neuronal types in
the cortex and spinal cord. The resulting extended DA–VITE–FLETE model offers
an integrative perspective on corticospinal control of Parkinsonian voluntary movement.
The model accounts for most of the known empirical signatures of Parkinsonian
willful action.

Keywords:computational neuroscience, motor control
Subjects:B Subjects allied to Medicine > B140 Neuroscience
Divisions:College of Science > School of Computer Science
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ID Code:28786
Deposited On:29 Sep 2017 10:05

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