Opposite effects of high- and low-frequency transcranial random noise stimulation probed with visual motion adaptation

Campana, Gianluca and Camilleri, Rebecca and Moret, Beatrice and Ghin, Filippo and Pavan, Andrea (2016) Opposite effects of high- and low-frequency transcranial random noise stimulation probed with visual motion adaptation. Scientific Reports, 6 (1). ISSN 2045-2322

Full content URL: http://dx.doi.org/10.1038/srep38919

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Abstract

Transcranial random noise stimulation (tRNS) is a recent neuro-modulation technique whose effects at both behavioural and neural level are still debated. Here we employed the well-known phenomenon of motion after-effect (MAE) in order to investigate the effects of high- vs. low-frequency tRNS on motion adaptation and recovery. Participants were asked to estimate the MAE duration following prolonged adaptation (20 s) to a complex moving pattern, while being stimulated with either sham or tRNS across different blocks. Different groups were administered with either high- or low-frequency tRNS. Stimulation sites were either bilateral human MT complex (hMT+) or frontal areas. The results showed that, whereas no effects on MAE duration were induced by stimulating frontal areas, when applied to the bilateral hMT+, high-frequency tRNS caused a significant decrease in MAE duration whereas low-frequency tRNS caused a significant corresponding increase in MAE duration. These findings indicate that high- and low-frequency tRNS have opposed effects on the adaptation-dependent unbalance between neurons tuned to opposite motion directions, and thus on neuronal excitability.

Keywords:Low frequency transcranial random noise stimulation (lf-tRNS), High frequency transcranial random noise stimulation (hf-tRNS), Complex motion, Motion adaptation, Motion after-effect, JCOpen
Subjects:C Biological Sciences > C850 Cognitive Psychology
C Biological Sciences > C830 Experimental Psychology
Divisions:College of Social Science > School of Psychology
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ID Code:27477
Deposited On:09 May 2017 12:45

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