Automated brain tumour detection and segmentation using superpixel-based extremely randomized trees in FLAIR MRI

Soltaninejad, Mohammadreza and Yang, Guang and Lambrou, Tryphon and Allinson, Nigel and Jones, Timothy and Barrick, Thomas and Howe, Franklyn and Ye, Xujiong (2017) Automated brain tumour detection and segmentation using superpixel-based extremely randomized trees in FLAIR MRI. International Journal of Computer Assisted Radiology and Surgery . ISSN 1861-6410

Full content URL: http://link.springer.com/article/10.1007/s11548-01...

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Abstract

Purpose: We propose a fully automated method for detection and segmentation of the abnormal tissue associated with brain tumour (tumour core and oedema) from Fluid Attenuated Inversion Recovery (FLAIR) Magnetic Resonance Imaging (MRI).
Methods: The method is based on superpixel technique and classification of each superpixel. A number of novel image
features including intensity-based, Gabor textons, fractal analysis and curvatures are calculated from each superpixel
within the entire brain area in FLAIR MRI to ensure a robust classification. Extremely randomized trees (ERT) classifier is compared with support vector machine (SVM) to classify each superpixel into tumour and non-tumour.
Results: The proposed method is evaluated on two datasets: (1) Our own clinical dataset: 19 MRI FLAIR images of patients with gliomas of grade II to IV, and (2) BRATS 2012 dataset: 30 FLAIR images with 10 low-grade and 20 highgrade
gliomas. The experimental results demonstrate the high detection and segmentation performance of the proposed
method using ERT classifier. For our own cohort, the average detection sensitivity, balanced error rate and the Dice overlap measure for the segmented tumour against the ground truth are 89.48%, 6% and 0.91, respectively, while, for the BRATS dataset, the corresponding evaluation results are 88.09 %, 6 % and 0.88, respectively.
Conclusions: This provides a close match to expert delineation across all grades of glioma, leading to a faster and
more reproducible method of brain tumour detection and delineation to aid patient management.

Keywords:Brain tumour segmentation, Extremely randomized trees, Feature selection, Magnetic resonance imaging, Superpixels, Textons
Subjects:G Mathematical and Computer Sciences > G400 Computer Science
Divisions:College of Science > School of Computer Science
ID Code:25561
Deposited On:06 Jan 2017 11:46

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