Using cyber-infrastructure for dynamic data driven laser treatment of cancer

Bajaj, C, and Oden, J. T. and Diller, K. R. and Browne, J. C. and Hazle, J. and Babuska, I. and Bass, J. and Bidaut, Luc and Demkowicz, L. and Elliott, A. and Feng, Y. and Fuentes, D. and Kwon, B. and Prudhomme, S. and Stafford, R. J. and Zhang, Y. (2007) Using cyber-infrastructure for dynamic data driven laser treatment of cancer. In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Springer, Beijing, pp. 972-979. ISBN 9783540725831

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Hyperthermia based cancer treatments are used to increase the susceptibility of cancerous tissue to subsequent radiation or chemotherapy treatments, and in the case in which a tumor exists as a well-defined region, higher intensity heat sources may be used to ablate the tissue. Utilizing the guidance of real-time treatment data while applying a laser heat source has the potential to provide unprecedented control over the outcome of the treatment process 6,12. The goals of this work are to provide a working snapshot of the current system architecture developed to provide a real-time finite element solution of the problems of calibration, optimal heat source control, and goal-oriented error estimation applied the equations of bioheat transfer and demonstrate that current finite element technology, parallel computer architecture, peer-to-peer data transfer infrastructure, and thermal imaging modalities are capable of inducing a precise computer controlled temperature field within the biological domain. © Springer-Verlag Berlin Heidelberg 2007.

Additional Information:Conference of 7th International Conference on Computational Science, ICCS 2007 ; Conference Date: 27 May 2007 Through 30 May 2007; Conference Code:70823
Keywords:Chemotherapy, Computer control, Heat transfer, Laser applications, Radiotherapy, Real time systems, Cancerous tissue, Cyber-infrastructure, Laser treatment, Oncology
Subjects:G Mathematical and Computer Sciences > G400 Computer Science
B Subjects allied to Medicine > B800 Medical Technology
Divisions:College of Science > School of Computer Science
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ID Code:24146
Deposited On:21 Oct 2016 09:45

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