DNA-directed spatial assembly of photosynthetic light-harvesting proteins

Henry, Sarah L. and Withers, Jamie M. and Singh, Ishwar and Cooper, Jonathan M. and Clark, Alasdair W. and Burley, Glenn A. and Cogdell, Richard J. (2015) DNA-directed spatial assembly of photosynthetic light-harvesting proteins. Organic & Biomolecular Chemistry, 14 (4). pp. 1359-1362. ISSN 1477-0520

Documents
OBC_2016_c5ob02351c.pdf

Request a copy
[img] PDF
OBC_2016_c5ob02351c.pdf - Whole Document
Restricted to Repository staff only

958kB
Item Type:Article
Item Status:Live Archive

Abstract

This manuscript describes the surface immobilization of a light-harvesting complex to
prescribed locations directed by the sequence-selective recognition of duplex DNA. An
engineered light-harvesting complex (RC-LH1) derived from Rhodopseudomonas (Rps.)
palustris containing the zinc finger (ZF) domain zif268 was prepared. The zif268 domain
directed the binding of zfRC-LH1 to target double-stranded DNA sequences both in solution
and when immobilized on lithographically defined micro-patterns.

Keywords:DNA, Light harvesting protein, click chemistry, NotOAChecked
Subjects:F Physical Sciences > F163 Bio-organic Chemistry
Divisions:College of Science > School of Pharmacy
Related URLs:
ID Code:22496
Deposited On:17 Mar 2016 09:36

Repository Staff Only: item control page