Laser melting of NiTi and its effects on in-vitro mesenchymal stem cell responses

Waugh, David and Lawrence, Jonathan and Chan, C. W. and Hussain, Issam and Man, H. C. (2014) Laser melting of NiTi and its effects on in-vitro mesenchymal stem cell responses. In: Laser surface engineering: processes and applications. Series in Electronic and Optical Materials . Woodhead Publishing, Cambridge. ISBN UNSPECIFIED

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Item Type:Book Section
Item Status:Live Archive

Abstract

Control of cell adhesion to synthetic polymers is a key factor in tissue engineering. The bioactivity of NiTi after laser melting was investigated implementing in vitro techniques for studying mesenchymal stem cell (MSC) responses. The effects of physical (surface roughness and topography) and chemical (surface Ti/Ni ratio) modifications as a consequence of laser melting on the cell morphology and cell coverage were studied. The results indicate that MSC morphology was affected primarily by topographical factors. No toxic effect in terms of Ni release affected the MSCs, as evidenced by the adhesion and spreading of the cells

Keywords:mesenchymal stem cell (MSC), tissue engineering, bioactivity of NiTi, laser
Subjects:B Subjects allied to Medicine > B830 Biomechanics, Biomaterials and Prosthetics (non-clinical)
C Biological Sciences > C130 Cell Biology
Divisions:College of Science > School of Life Sciences
ID Code:19927
Deposited On:09 Jan 2016 22:25

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