Water-soluble aryl-extended calix[4]pyrroles with unperturbed aromatic cavities: synthesis and binding studies

Hernández-Alonso, D. and Zankowski, S. and Adriaenssens, L. and Ballester, P. (2015) Water-soluble aryl-extended calix[4]pyrroles with unperturbed aromatic cavities: synthesis and binding studies. Organic & Biomolecular Chemistry, 13 (4). pp. 1022-1029. ISSN 1477-0520

Full content URL: http://dx.doi.org/10.1039/c4ob02108h

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Abstract

We report the synthesis of a novel, water-soluble aryl-extended calix[4]pyrrole receptor. The water-solubilising groups are placed at the lower rim of the receptor, leaving the binding pocket unperturbed and open for modification. Binding studies were performed with a series of pyridine N-oxides. These studies revealed the ability of the receptor to bind neutral and charged N-oxides in basified water with stability constants higher than 104 M−1

Additional Information:This article is part of themed collection: Supramolecular Chemistry in Water
Keywords:host-guest, water, JCOpen
Subjects:F Physical Sciences > F160 Organic Chemistry
F Physical Sciences > F100 Chemistry
Divisions:College of Science > School of Chemistry
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ID Code:18423
Deposited On:20 Aug 2015 14:44

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