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Geographical distribution and epidemiological features of Old World Leishmania infantum and Leishmania donovani foci, based on the isoenzyme analysis of 2277 strains

Pratlong, Francine and Lami, Patrick and Ravel, Christophe and Balard, Yves and Dereure, Jacques and Serres, Ghislaine and El baidouri, Fouad and Dedet, Jean-Pierre (2013) Geographical distribution and epidemiological features of Old World Leishmania infantum and Leishmania donovani foci, based on the isoenzyme analysis of 2277 strains. Parasitology, 140 (04). pp. 423-434. ISSN 0031-1820

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Item Type:Article
Item Status:Live Archive

Abstract

A series of 2277 Leishmania strains from Old World visceral leishmaniasis foci, isolated between 1973 and 2008, were studied by isoenzyme analysis. The strains were obtained from humans, domestic and wild carnivores, rodents and phlebotomine sandflies, and came from 36 countries. In all, 60 different zymodemes were identified and clustered by a phenetic analysis into 3 different groups corresponding to the typically visceralizing species L. donovani (20 zymodemes, 169 strains), L. archibaldi (3 zymodemes, 46 strains) and L. infantum (37 zymodemes, 2,062 strains). The taxonomic position of these isoenzymatic groups is discussed in view of contradictory results obtained from recent molecular studies

Keywords:Visceral leishmaniasis, Leishmania infantum, Leishmania donovani, Isoenzymatic identification, Old World
Subjects:C Biological Sciences > C111 Parasitology
Divisions:College of Science
ID Code:16908
Deposited On:10 Mar 2015 14:57

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