Vibrational spectroscopic study of salbutamol hemisulphate

Ali, H. R. H. and Edwards, H. G. M. and Kendrick, J. and Scowen, I. J. (2009) Vibrational spectroscopic study of salbutamol hemisulphate. Drug Testing and Analysis, 1 (1). pp. 51-56. ISSN 1942-7603

Full content URL: http://dx.doi.org/10.1002/dta.8

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Item Type:Article
Item Status:Live Archive

Abstract

Salbutamol hemisulphate is a relatively selective β 2-adrenergic agonist and is used as a bronchodilator. In this work, we present a detailed vibrational spectroscopic investigation of salbutamol hemisulphate using mid-infrared and near-infrared Fourier-transform (NIR-FT) Raman spectroscopies. These data are supported by quantum chemical calculations, which allow us to characterise the vibrational spectra of this compound reasonably. As such, this study could be viable for examining the way in which this drug interacts with its targetmolecules. Copyright © 2009 John Wiley & Sons, Ltd.

Keywords:salbutamol sulfate, analytic method, article, data analysis, drug binding, drug structure, infrared spectroscopy, near infrared spectroscopy, priority journal, quantum chemistry, Raman spectrometry, spectroscopy, vibrational spectroscopy, Adrenergic beta-Agonists, Albuterol, Bronchodilator Agents, Quantum Theory, Spectroscopy, Fourier Transform Infrared, Spectrum Analysis, Raman
Subjects:F Physical Sciences > F100 Chemistry
Divisions:College of Science > School of Chemistry
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ID Code:13045
Deposited On:19 Mar 2014 19:15

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