Unique mitochondrial DNA in highly inbred feral cattle

Hudson, Gavin and Wilson, Ian and Payne, Brendan I. A. and Elson, Joanna and Samuels, David C. and Santibanez-Korev, Mauro and Hall, Stephen J. G. and Chinnery, Patrick F. (2012) Unique mitochondrial DNA in highly inbred feral cattle. Mitochondrion, 12 (4). pp. 438-440. ISSN 1567-7249

Full content URL: http://dx.doi.org/10.1016/j.mito.2012.05.003

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Abstract

The Chillingham herd of wild Northumbrian cattle remains viable despite over 300 years of in-breeding and a near-homozygous nuclear genome. Here we report the complete mitochondrial DNA sequence using ultra-deep next generation sequencing. Random population sampling of ~10% of the extant herd identified a single mtDNA haplotype harbouring a unique bovine variant present in all other higher mammals (m.11789C/Y421H) which may contribute to their survival.

Keywords:mtDNA, Mitochondria, Bovine
Subjects:C Biological Sciences > C180 Ecology
C Biological Sciences > C432 Veterinary Genetics
Divisions:College of Science > School of Life Sciences
ID Code:12861
Deposited On:08 Jan 2014 15:17

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