Aberrations of human gender identification by amelogenin test in Libyans (Benghazi city)

Elmrghni, Samir and Shaw, Michael and Ali, Nadir and Dixon, Ron and Ross Williams, D. (2012) Aberrations of human gender identification by amelogenin test in Libyans (Benghazi city). Indian Journal of Forensic Medicine and Toxicology, 6 (2). pp. 163-166. ISSN 0973-9122

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Item Type:Article
Item Status:Live Archive

Abstract

Gender identification is essential in forensic science to provide the initial information for criminal investigation. However, gender identification by amplification of amelogenin gene sometimes showed controversial cases, in which male samples was falsely identified as females and female samples was recorded as males. We reported the anomalous amelogenin results of 2 male samples (out of 238 males) represented as females (Y deletions) and another 2 samples with (X deletions) in Benghazi (Libya). The frequency in both was about 0.8. Higher than those of the other populations reported.To confirm amelogenin results of the 2 controversial samples, DNA was further used in SRY and Y-STR typing. All samples typed as males but two showed with X chromosomes. From the results, it was highly suggested that for the controversial cases of human gender identification with amelogenin tests, amplification of SRY gene or/and Y-STR markers will be adopted to confirm the gender.

Keywords:amelogenin, DNA, article, chromosome aberration, chromosome deletion X, chromosome deletion Y, controlled study, female, gender identity, human, Libyan Arab Jamahiriya, major clinical study, male, SRY gene, X chromosome
Subjects:C Biological Sciences > C420 Human Genetics
Divisions:College of Science > School of Life Sciences
ID Code:11027
Deposited On:19 Dec 2013 15:03

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